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Fermentation

Olon is a global provider of high-quality services in the field of custom microbial process development and manufacturing, with a total fermentation capacity of 4.500 m³, based on 65 fermenters, spread between two manufacturing locations in Italy. Olon also has a manufacturing site in India with a fermentation capacity of 400 m³ as well as Chemical synthesis plant with reaction capacity of 170 m³. We offer dedicated solutions for peptides, proteins, enzymes and specialty small molecules, focused on applications in pharma, food and bio-industrial, for clients in Europe as well as United States.

Our expertise is based on working with a variety of microbes, ranging from yeast (Saccharomyces, P. Pastoris) to bacteria (E.coli, Bacillus, Streptomyces) to fungi (Aspergillus, Trichoderma).

R&D

Highly experienced R&D team to deliver solutions to critical and complex projects to each development phase, from familiarization to robust commercial scale production through process development. Strong know-how in strain development / improvement as well as in fermentation parameters optimization and DSP process development.

Technologies

Pharma: Olon has dedicated manufacturing areas and equipment for pharmaceutical products (including areas for HPC). The sites operate under cGMP and is FDA. We are annually audited by FDA, AIFA (EMA) and by other authorities form over the world.

Food: Olon has dedicated manufacturing areas for technical and food-grade products. We are GFSI (FSSC 22.000) and ISO 14001 certified and can manage kosher, halal and allergen free quality requirements.

Downsteam Processing Technologies

  • Centrifugation
  • Filtration (UF, DF, MF, NF, filter press)
  • Homogenization
  • Chromatography (including reverse phase and preparative HPLC)
  • Crystallization
  • Solvent recovery/recycle
  • Drying (incl freeze-drying and spray-drying)

Manufacturing Site

  • OLON SETTIMO TORINESE (TO) – Italy
  • CAPUA BIOSERVICES (CE) – Italy
  • OLON A.P.I. INDIA PVT.LTD (Mahad) – India
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